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The big piano that Tom Hanks plays in the toy store is FAO Schwartz.
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The house the younger version of Tom Hank's character lives in.
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This is where the big Josh Baskin find the Zoltar the Magnificent machine in order to wish himself small again. The location, Playland Amusement Park, was also used in The Muppets Take Manhattan, Fatal Attraction and Music and Lyrics
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Southwest Corner, Grand Street and Greene Street